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How the Worker Shortage in Healthcare Could Impact Your Health

YourUpdateTV

A recent Harris Poll found that 68% of Americans are worried that the worker shortage in healthcare could have an impact on their own health. Recently, spokespeople from the American Academy of Physician Associates (AAPA), participated in nationwide satellite media tour to discuss the impact of the worker shortage in healthcare and how physician associates, or PAs, can help increase access to care. A video accompanying this announcement is available at: https://youtu.be/4XRJDYFt3R0 Healthcare workforce shortages are having a profound impact on patient access to care, with patients reporting feeling frustrated and anxious about their ability to get the care they need when they need it. The recent Harris Poll survey found that nearly three-fourths of all U.S. adults say the healthcare system isn’t meeting their needs, and more than 1 in 4 gave the healthcare system a failing grade. One of the most concerning ways provider shortages are impacting patients is the amount of time it is taking to get a needed health appointment. Patients are waiting an average of 3.9 weeks for a medical appointment. As one of the fastest growing medical professions in the country, PAs can make a positive and lasting impact on patient care. An overwhelming 91% of U.S. adults believe that PAs are part of the solution to addressing the shortage of healthcare providers and additionally, 90% of patients say that PAs increase access to care and make medical appointments easier to obtain. One significant issue is that PA practice laws vary by state across the country. The challenge here is that in far too many states, these laws haven't been updated to reflect the way medical care is delivered today. A resounding 91% of U.S. adults support updating PA practice laws and the mandate is clear: The public wants the healthcare system to be as efficient and accessible as possible and updating these laws is a win-win for patients and the entire healthcare system. For more information, please visit aapa.org/patientexperience. About the American Academy of Physician Associates (AAPA) AAPA is the national membership organization for all physician associates/physician assistants (PAs). PAs are licensed clinicians who practice medicine in every specialty and setting. Trusted, rigorously educated and trained healthcare professionals, PAs are dedicated to expanding access to care and transforming health and wellness through patient-centered, team-based medical practice. PA has been named one of the best jobs overall and one of the best healthcare jobs for the sixth year in a row by U.S. News & World Report The PA profession ranked number three this year in Best STEM jobs. Learn more about the profession at aapa.org and engage through Facebook, LinkedIn, Instagram, and Twitter. Contact Details YourUpdateTV +1 212-736-2727 yourupdatetv@gmail.com

October 18, 2023 02:31 PM Eastern Daylight Time

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Redx Pharma has "a lot to be excited about" after successful fundraise

Redx Pharma PLC

Redx Pharma PLC (AIM:REDX) Chief Financial Officer Peter Collum speaks to Thomas Warner from Proactive after the clinical-stage biotechnology company announced a £14.1mln fundraise from existing investors that will take its working capital to more than £28mln. Collum explains that the additional funding will extend the company's cash runway from early 2024 into the third quarter, enabling them to achieve critical milestones in their portfolio development plan. He says that one of the key highlights is the Phase 2a data release for their lead asset, the selective ROCK2 inhibitor known as Zelasudil, with a focus on treating Idiopathic Pulmonary Fibrosis (IPF). IPF is a severe lung condition with limited treatment options, making this development crucial for patients. Additionally, Redx Pharma is initiating a Phase 1 trial for their oral pan-ROCK inhibitor, RXC008, targeting Fibrostenosis in Crohn's disease patients. This innovative approach offers hope to patients facing invasive surgery as the only current treatment option. Collum emphasises Redx Pharma's strong track record of developing high-quality small molecule compounds, attracting collaborations with prominent pharmaceutical companies. With a pipeline of promising assets, he says that the company "has a lot going on and a lot to be excited about for the future." Contact Details Proactive UK Ltd +44 20 7989 0813 uk@proactiveinvestors.com

October 18, 2023 12:15 PM Eastern Daylight Time

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Centre for Neuro Skills Announces New Houston Medical Director

Centre for Neuro Skills

Centre for Neuro Skills (CNS), a leader in traumatic brain injury and stroke rehabilitation services, today announced the appointment of Dr. Natasha Rose, M.D., as Medical Director of CNS’ Houston clinic. “Dr. Rose has an extensive medical background working with post-acute brain injury patients and overseeing in-patient rehabilitation units,” says Dr. Matthew Ashley, Chief Medical Officer of Centre for Neuro Skills. “We are thrilled to have her on our team, leading the charge in Houston.” As Medical Director for CNS’ state-of-the-art rehabilitation clinic in Houston, Texas, Dr. Rose joins a highly-trained clinical staff dedicated to treating traumatic brain injury and stroke patients. Dr. Rose will provide medical oversight and collaborate with case managers, therapists and specialists to oversee patient care and create neurorehabilitation programs. Dr. Rose received her medical degree from the University of Michigan in Ann Arbor. She completed a transitional year at Oakwood Hospital and her physical medicine and rehabilitation residency at Baylor College. Her fellowship focused on brain injury and stroke patients. Dr. Rose is also a member of the American Academy of Physical Medicine and Rehabilitation. The CNS Houston clinic is located in Webster, just 20 minutes south of downtown Houston. CNS has three other clinics across Texas in Dallas, Fort Worth and Austin, as well as three California clinics in Los Angeles, San Francisco and Bakersfield. Each clinic offers unique environments that provide excellent preparation for community reintegration. All CNS clinics share the common goal of providing quality neurorehabilitation therapy through inpatient, outpatient, day treatment and residential rehabilitation programs. “I’ve always felt that I could help people through my role as a physician,” said Dr. Rose. “I look forward to advancing patient care and outcomes through CNS’ specialized neurorehabilitation programming.” *** About Centre for Neuro Skills Centre for Neuro Skills is an experienced and respected world leader in providing intensive rehabilitation and medical programs for those recovering from all types of brain injury. CNS covers a full spectrum of advanced care from residential and assisted living to outpatient/day treatment. Founded by Dr. Mark Ashley in 1980, CNS has seven locations in California and Texas. For more information about Centre for Neuro Skills, visit: www.neuroskills.com, Facebook, Twitter, LinkedIn, YouTube. Media, please note: Visual assets, including photos, are available. To request an interview with CNS leadership or clinical staff, please contact Robin Carr at 415.766.0927 or CNS@landispr.com. # # # Contact Details Landis Communications Inc. Robin Carr +1 415-766-0927 cns@landispr.com Company Website https://www.neuroskills.com/

October 18, 2023 08:01 AM Pacific Daylight Time

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PathAI Announces Launch of AIM-TumorCellularity (AIM-TC), an AI-Based Tumor Cellularity Assessment Product to Inform Advanced Molecular Testing

PathAI

PathAI, a global leader in AI-powered pathology, today announced the launch of AIM-TumorCellularity (AIM-TC), the latest algorithm product available for use by laboratories utilizing the AISight Image Management System (IMS). 1 AIM-TC enables automated assessment of tumor cellularity, or tumor fraction, which is utilized to determine if there is sufficient tumor tissue to support advanced next generation sequencing (NGS) testing. Insufficient tumor DNA is a common failure mode in comprehensive genomic profiling and results in the destruction of precious tissue without molecular biomarker information to inform care decisions. AIM-TC solves for this by running on a standard hematoxylin and eosin (H&E) whole slide image and can automatically determine the tumor area and percentage of tumor nuclei. “As a molecular pathologist myself, I know how important accurate tumor cellularity assessment is. Many laboratories struggle with high NGS failure rates due to insufficient tumor content in the sample, leading to wasted time and expense.” said Andy Beck M.D. Ph.D., Chief Executive Officer and Co-Founder of PathAI. “Because of this, it’s become standard practice for pathologists to manually assess tumor fraction. We now have the opportunity to automate this step with AI, allowing pathologists to focus on other tasks.” Tumor cellularity assessment can be time consuming and onerous, particularly when the tumor content is low. 2,3 For high volume laboratories, AIM-TC can reduce the amount of pathologist time spent on tumor cellularity assessments while also providing standardized, quantitative metrics to support more accurate determination of the required tissue inputs. “AIM-TC is a great example of how AI can augment the pathology laboratory and eliminate routine, stressful and time-consuming activities, allowing pathologists to focus on what they do best,” said Tobias Kull, PhD., bioinformatician in the Molecular Pathology Unit of University Hospital Zurich. “We expect that if implemented widely in our practice, AIM-TC can save hundreds of hours of pathologist time that can instead be used for case sign-off and patient care.” AIM-TC is currently available in Non-Small Cell Lung Cancer (NSCLC) and will be launched in 12 additional tumor types (including breast cancer, colorectal cancer, prostate cancer, gastric cancer, pancreatic cancer, ovarian cancer, melanoma, renal cell carcinoma, hepatocellular carcinoma, and urothelial carcinoma) in the coming months. To learn more about AISight, PathAI’s Image Management System, or AIM-TC, please visit our website, request a meeting with our team, or visit us at PathVisions in Orlando, Florida (Booth #206; October 29-31, 2023). 1 AIM Tumor Cellularity and AISight are Research Use Only. Not for use in diagnostic procedures. 2 Smits AJ, et al. The estimation of tumor cell percentage for molecular testing by pathologists is not accurate. Mod Pathol. 2014 Feb;27(2):168-74. 3 Viray H, et al. A prospective, multi-institutional diagnostic trial to determine pathologist accuracy in estimation of percentage of malignant cells. Arch Pathol Lab Med. 2013 Nov;137(11):1545-9. About PathAI PathAI is the only AI-focused technology company to provide comprehensive precision pathology solutions from wet lab services to algorithm deployment for clinical trials and laboratory use. Rigorously trained and validated with data from more than 15 million annotations, its AI-powered models can be leveraged to optimize the analysis of pathology samples to improve efficiency and accuracy of pathology interpretation, as well as to better gauge therapeutic efficacy and accelerate drug development for complex diseases. PathAI, which is headquartered in Boston, MA, and operates a CAP/CLIA-certified laboratory in Memphis, TN, is proud to have a team of 600+ innovative thinkers from around the globe. For more information, please visit www.pathai.com. Contact Details SVM Public Relations and Marketing Communications Maggie Naples +1 401-490-9700 pathai@svmpr.com Company Website https://www.pathai.com/

October 18, 2023 10:00 AM Eastern Daylight Time

Poolbeg Pharma unveils new collaboration agreement

Poolbeg Pharma PLC

Poolbeg Pharma PLC (AIM:POLB, OTCQB:POLBF) CEO Jeremy Skillington speaks to Thomas Warner from Proactive after announcing the pharma & biotech company has signed a new collaboration agreement with an unspecified NASDAQ-listed biopharma company. He explains that the collaboration is aimed at developing an optimized oral drug for metabolic conditions, with Poolbeg receiving funding to produce a prototype drug encapsulating one of the partner's drugs for the same condition. The focus is on improving drug delivery and achieving the ideal site of action, which could enhance efficacy and safety. Skillington expresses optimism about the collaboration potentially evolving into a full licensing agreement, highlighting the goal of generating early revenues for Poolbeg. The partnership's core attraction lies in Poolbeg's validated encapsulation technology, which is believed to enhance the partner's products' bioavailability and effectiveness. The CEO emphasises the significance of delivering drugs to their ideal site of action, particularly for metabolic diseases. By targeting the drug orally to the precise location of action, it can lead to reduced dosage requirements and improved safety. He says that Poolbeg continues to work on various initiatives, including the orange GLP-1 program and an oral vaccine program funded by the Irish government. The move towards oral delivery aims to enhance convenience for patients and expand the company's reach beyond traditional injectable treatments. Contact Details Proactive UK Ltd +44 20 7989 0813 uk@proactiveinvestors.com

October 18, 2023 06:21 AM Eastern Daylight Time

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Mydecine Innovations Group gearing up for human trials after completing Aquis listing

Mydecine Innovations Group Inc

Mydecine Innovations Group Inc (OTC:MYCOF, NEO:MYCO) CEO Joshua Bartch speaks to Thomas Warner from Proactive London about the biotechnology company's ambitious goals in the psychedelic medicine sector. Bartch explains that Mydecine focuses on developing "second generation" drugs derived from first-generation psychedelic molecules like LSD, MDMA, and psilocybin. Their aim is to enhance the efficacy of these drugs while addressing challenges like half-life, scalability, cost, and accessibility. He emphasises the company's efforts to make these drugs more adaptable to the existing medical infrastructure, aiming to increase accessibility by five to tenfold. Highlighting the UK's progressive stance on psychedelics, Bartch announced Mydecine's recent listing on London's Aquis Exchange, emphasising the potential benefits for both current and future shareholders. The company is gearing up for phase one human trials of their lead drug candidates by early 2024, with their MYCO-006, a second-generation MDMA analogue, showing promising results in preclinical studies. Addressing perceptions of psychedelic medicine industry, Bartch notes a significant shift, saying that major biotech investors and institutions, once skeptical, are now showing keen interest. Contact Details Proactive United States Proactive United States +1 347-449-0879 action@proactiveinvestors.com

October 18, 2023 06:15 AM Eastern Daylight Time

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Dr. Wolff’s Vagisan introduces hormone-free Moisturising Cream and Moisturising Cremolum, clinically proven to soothe vaginal dryness

Dr. Wolff

HONG KONG SAR - Media OutReach - 18 October 2023 - Many woman experiencing menopause are troubled by vaginal dryness. It can cause discomfort when sitting, standing, exercising, during urinating and even working, and can greatly impact their quality of life. In Hong Kong, every 2 out of 3 women has experienced symptoms of Vaginal Dryness 1. Yet, it remains a taboo topic, making it difficult for women to discuss their intimate health concerns with family, friends, or doctors, resulting in only one-quarter of affected woman seeking treatment 2. Vaginal secretions gradually decrease as a woman ages, resulting in decreased lubrication and elasticity of the vaginal tissue. This can result in vaginal dryness and associated symptoms such as dryness, itching, burning, and pain 3. Given that these symptoms closely resemble those associated with other vaginal flora issues, many women have been perplexed and resorted to over-the-counter remedies, which may exacerbate the situation 2. Symptoms of vaginal dryness can also be mistaken for poor hygiene. In fact, excessive cleansing of the intimate area with conventional soaps and vaginal douching, may risk irritating the vaginal skin and disrupt the vaginal flora, leading to worsening of the condition. Soothing Vaginal Dryness with the right products Dr Dawn Harper, a general practitioner in United Kingdom known for her expertise on menopause, emphasises on the importance for women suffering from vaginal dryness to use a moisturising cream with high water content and lipids which can provide lasting soothing relief for women experiencing Vaginal Dryness. Introducing Hormone-Free Dr. Wolff’s Vagisan Moisturising Cream and Moisturising Cremolum Dr. Wolff’s Vagisan Moisturising Cream Effectively relieves dryness, itching, burning and pain associated with vaginal dryness Contains high water content and soothing lipids, keeps skin of intimate area soft and supple Contains lactic acid and is thus adjusted to the healthy pH level in the vagina Hormone-free and can be applied intravaginally and to the external genital area Clinically proven to relieve symptoms of vaginal dryness Dr. Wolff’s Vagisan Moisturising Cream can not only moisturises the internal and external skin of the vagina, but also supplies it with nourishing lipids, leaving the skin of the intimate area supple and soft. Several clinical studies have been performed with Dr. Wolff’s Vagisan Moisturising Cream, proving its efficacy and tolerability. Not only did the cream show superior efficacy as well as tolerability as compared to a water-based non-hormonal gel 4, but it was statistically significantly non-inferior to a hormone-containing cream (estriol 0.1%) in terms of improvement on subjective symptoms of vaginal dryness 5. Also available as an innovative pessary for greater convenience without the use of an applicator: Dr. Wolff’s Vagisan Moisturising Cremolum Smooth melting pessary, forms into a cream in the vagina together with vaginal fluids Individually wrapped for more hygiene and convenience Hormone-free and can be applied intravaginally Free from preservatives A Dr.Wolff’s clinical study 6 also found that the Dr. Wolff’s Vagisan Moisturising Cremolum provided a long-lasting soothing effect that lasted 3 days or longer for majority of participants. It significantly improves the symptoms of dryness, itching, burning, and pain associated with vaginal dryness and provides relief from first application, allowing these women to achieve a better quality of life. Furthermore, 90% of test participants rated the moisturising cremolum as very easy or simple to use. For more questions on the products mentioned above, please refer to Dr. Wolff’s Vagisan official site: https://www.vagisan.hk/ 1 Survey Aug 2016, Vaginal Dryness, n=400 Hong Kong women (aged 41-55), conducted by AIP Global, Singapore 2 Womens’s Health Concern (2022,) https://www.womens-health-concern.org/wp-content/uploads/2022/12/25-WHC-FACTSHEET-VaginalDryness-NOV2022-B.pdf 3 Family Health Service (2022, February) https://www.fhs.gov.hk/english/health_info/woman/14768.html 4 Stute, P., May, T. W., Masur, C., & Schmidts-Winkler, I. M. (2015). Efficacy and safety of non-hormonal remedies for vaginal dryness: open, prospective, randomized trial. Climacteric: the journal of the International Menopause Society, 18(4), 582–589. https://doi.org/10.3109/13697137.2015.1036854 5 Garcia de Arriba, S., Grüntkemeier, L., Häuser, M., May, T. W., Masur, C., & Stute, P. (2022). Vaginal hormone-free moisturising cream is not inferior to an estriol cream for treating symptoms of vulvovaginal atrophy: Prospective, randomised study. PloS one, 17(5), e0266633. https://doi.org/10.1371/journal.pone.0266633 6 Clinical trial over 6 weeks with n=79 postmenopausal women with vaginal dryness ( https://clinicaltrials.gov/study/NCT05211505?intr=cremolum&rank=1&tab=table ) About Dr. Wolff Founded in 1905, Dr. Wolff is one of the largest medium-sized family-owned businesses in the Germany. The Dr. Wolff Group consists of the owner-managed companies Dr. Kurt Wolff, Dr. August Wolff and their international subsidiaries. Distinguished by the development and creative marketing of real innovations for more than 100 years, the company concentrates on products which embody verifiable advantages for consumers.For more information, please visit: Dr. Wolff Group ( drwolffgroup.com ) Contact Details Dr. Wolff Singapore Caliente Tong caliente.tong@dr-wolff.sg

October 18, 2023 04:28 AM Eastern Daylight Time

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Contract Management Associations Join Forces to Globally Elevate Profession

National Contract Management Association

Reston, VA and Ridgefield, CT – October 17, 2023 – Today, the National Contract Management Association (NCMA) and World Commerce and Contracting (WorldCC), the world's foremost authorities in the field of contract management, proudly announce a groundbreaking joint venture. This partnership is set to revolutionize the profession around the world. Contract management is the bedrock of successful business and social outcomes, underpinning transactions that drive economies and society forward. Recognizing the paramount importance of this profession, WorldCC and NCMA are uniting to advance a common and worldwide understanding of both public and commercial contracting practices. One of the core pillars of this joint venture is the commitment to consensus-based updates. At its heart, this collaboration aims to continually refine and expand the application of the Contract Management Standard™ (CMS™). By harnessing their collective expertise, they intend to adapt the CMS™ to accurately reflect the ever-evolving landscape of contract management in today's intricate global context and drive the growing adoption of the CMS™ for academic recognition of contract management. In addition to CMS™, this partnership will provide a wealth of guidance resources that are invaluable to professionals in the field. These resources will focus on the utilization of artificial intelligence (AI) technologies within the realm of contract management. This initiative is poised to empower practitioners by unlocking the full potential of AI, leading to enhanced efficiency, precision, and innovative practices. Sally Guyer, WorldCC's Chief Executive Officer, emphasized the collaborative spirit of the venture. "Our shared vision is to elevate the profession of contract management and ensure that it remains at the forefront of industry practices. By unifying our efforts, we can deliver cutting-edge guidance and resources that will empower professionals worldwide." NCMA's Chief Executive Officer, Kraig Conrad, expressed his enthusiasm for this milestone partnership, stating, "This joint venture marks a new era for contract management professionals. Together, we'll elevate CMS™ globally, setting a new standard for excellence and creating a common contracting language." The announcement was made at WorldCC's Americas Summit in Dallas TX. Further details will be discussed at NCMA's Government Contract Management Symposium November 6th and 7th in Bethesda, MD. The National Contract Management Association (NCMA), a nonprofit professional society founded in 1959, is an important resource for contract management and its nexus with related acquisition communities. With nearly 20,000 members, NCMA is dedicated to promoting excellence in the practice and profession through education, certification, and networking opportunities. NCMA serves through an open exchange of ideas in neutral forums of buyers and sellers. Visit ncmahq.org to learn more. About WorldCC World Commerce & Contracting is a not-for-profit association dedicated to helping its global members achieve high-performing and trusted trading relationships. With 75,000 members from over 20,000 organizations across 180 countries, the association welcomes everyone with an interest in better contracting: business leaders, practitioners, experts, and newcomers. It is independent, provocative, and disciplined existing for its members, the contracting community and society at large. Visit worldcc.com to learn more. Contact Details National Contract Management Association Holly DeHesa +1 281-865-3296 holly.dehesa@ncmahq.org WorldCC Kate Hodgins media@worldcc.com Company Website https://www.ncmahq.org/

October 18, 2023 04:00 AM Eastern Daylight Time

Contract Management Associations Join Forces to Globally Elevate Profession

National Contract Management Association

Today, the National Contract Management Association (NCMA) and World Commerce and Contracting (WorldCC), the world's foremost authorities in the field of contract management, proudly announce a groundbreaking joint venture. This partnership is set to revolutionize the profession around the world. Contract management is the bedrock of successful business and social outcomes, underpinning transactions that drive economies and society forward. Recognizing the paramount importance of this profession, WorldCC and NCMA are uniting to advance a common and worldwide understanding of both public and commercial contracting practices. One of the core pillars of this joint venture is the commitment to consensus-based updates. At its heart, this collaboration aims to continually refine and expand the application of the Contract Management Standard™ (CMS™). By harnessing their collective expertise, they intend to adapt the CMS™ to accurately reflect the ever-evolving landscape of contract management in today's intricate global context and drive the growing adoption of the CMS™ for academic recognition of contract management. In addition to CMS™, this partnership will provide a wealth of guidance resources that are invaluable to professionals in the field. These resources will focus on the utilization of artificial intelligence (AI) technologies within the realm of contract management. This initiative is poised to empower practitioners by unlocking the full potential of AI, leading to enhanced efficiency, precision, and innovative practices. Sally Guyer, WorldCC's Chief Executive Officer, emphasized the collaborative spirit of the venture. "Our shared vision is to elevate the profession of contract management and ensure that it remains at the forefront of industry practices. By unifying our efforts, we can deliver cutting-edge guidance and resources that will empower professionals worldwide." NCMA's Chief Executive Officer, Kraig Conrad, expressed his enthusiasm for this milestone partnership, stating, "This joint venture marks a new era for contract management professionals. Together, we'll elevate CMS™ globally, setting a new standard for excellence and creating a common contracting language." The announcement was made at WorldCC's Americas Summit in Dallas TX. Further details will be discussed at NCMA's Government Contract Management Symposium November 6th and 7th in Bethesda, MD. For media inquiries, please contact: Holly DeHesa, NCMA Director of Marketing and Communications holly.dehesa@ncmahq.org Kate Hodgins, WorldCC Head of Marketing media@worldcc.com The National Contract Management Association (NCMA), a nonprofit professional society founded in 1959, is an important resource in the field of contract management. With nearly 20,000 members, NCMA is dedicated to promoting excellence in the practice and profession through education, certification, and networking opportunities. NCMA serves through an open exchange of ideas in neutral forums of buyers and sellers. Visit www.ncmahq.org to learn more. About WorldCC World Commerce & Contracting is a not-for-profit association dedicated to helping its global members achieve high-performing and trusted trading relationships. With 75,000 members from over 20,000 organizations across 180 countries, the association welcomes everyone with an interest in better contracting: business leaders, practitioners, experts, and newcomers. It is independent, provocative, and disciplined existing for its members, the contracting community and society at large. Visit worldcc.com to learn more. Contact Details NCMA Holly DeHesa +1 281-865-3296 holly.dehesa@ncmahq.org Company Website https://www.ncmahq.org/

October 17, 2023 10:00 AM Eastern Daylight Time

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