Digital Asset DirectHoliday Cheer gift ideas with Chassie Post
News Media Group, Inc.
Contact Details Karl Wayne +1 334-440-6397 karl@newsmg.com Company Website https://newsmg.com/
December 07, 2022 06:00 AM Eastern Standard Time
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Digital Asset Direct
News ReleaseTurn family moments into cherished memories
YourUpdateTV
This holiday season, whether you’re looking for gifts for your children, grandkids, friends or yourself, Nintendo Switch has gifts for all ages — and incredible games and experiences the entire family can enjoy. With Nintendo’s vast library of games, there is a game for everyone on the Nintendo Switch system. This includes fun multiplayer titles that the whole family can play together, in addition to incredible games and experiences you can only find on Nintendo Switch. A video accompanying this announcement is available at: https://youtu.be/wWekFk-Mcik With the Nintendo Switch family of systems, everyone has the choice of a system that best fits their needs and play styles. The Nintendo Switch system can be played on the TV, in Tabletop mode or taken on the go for portable play. The Nintendo Switch Lite system is a dedicated handheld gaming system great for those who love playing in handheld mode. The Nintendo Switch – OLED Model system is similar in overall size to the Nintendo Switch system, but features a larger, vibrant 7-inch OLED screen with vivid colors and crisp contrast. Here are some of the Nintendo Switch games people are talking about this year: The Splatoon 3 game is the newest addition to the Splatoon series, where players splash vivid ink everywhere using colorful, over-the-top weapons. The battlegrounds include new and returning stages for heated multiplayer Turf War* battles, where two teams attempt to cover the most ground with their ink color in three-minutes. Players can also pick a side and battle it out in three-team Splatfests**, compete for rankings in thrilling Anarchy Battles or swim solo in the new single-player Story Mode, “Return of the Mammalians.” Gameplay is fun for both parents and kids, who can play together across multiple Nintendo Switch systems or online including co-op modes like Salmon Run*. Families can get moving together with the Nintendo Switch Sports game, as they team up to play Soccer, Volleyball, Bowling, Tennis, Badminton, and Chambara (swordplay) using Joy-Con controllers. Plus, in late November, Nintendo released a new update that adds Golf to the lineup. Controls are intuitive, so it’s easy to jump in and get started. With controlled motions you can curve your bowling ball, add spin to a tennis shot or even use a Joy-Con with the included Leg Strap accessory to kick the ball in Soccer. Family and friends can join in on the fun on the same system (additional accessories may be required; sold separately) or online**. In Pokémon Scarlet and Pokémon Violet embark on a new, open-world Pokémon adventure through the rich and expansive Paldea region. Weave freely through three grand stories: Take on Gyms in Victory Road, battle Titan Pokémon in Path of Legends and challenge Team Star in Starfall Street. Ride a form-changing Legendary Pokémon to traverse the land, seas and skies of the Paldea Region. Parents that grew up with the original Pokémon games can now experience the game in a whole new way with the little trainers in their family. Plus, several Nintendo Switch games and DLC*** are sure to bring family fun this holiday, including Mario Kart 8 Deluxe, Mario Kart 8 Deluxe – Booster Course Pass DLC, Kirby and the Forgotten Land, Mario + Rabbids Sparks of Hope, Just Dance 2023 Edition, Sonic Frontiers in addition to a library of classic Nintendo 64 titles available for Nintendo Switch Online + Expansion Pack members. For more information, visit https://www.nintendo.com/store/holiday-gifts/. *Additional games, systems and/or Nintendo Switch Online membership required for multiplayer mode. Nintendo Switch Online membership and Nintendo Account required for online features. Membership auto-renews after initial term at the then-current price unless canceled. Not available in all countries. Internet access required for online features. Terms apply. nintendo.com/switch-online. Games, systems and Nintendo Switch Online memberships sold separately. **Any Nintendo Switch Online membership (sold separately) and Nintendo Account required for online features. Membership auto-renews after initial term at the then-current price unless canceled. Not available in all countries. Internet access required for online features. Terms apply. nintendo.com/switch-online ***Full version of game required to use DLC for that game. Sold separately. About Lilliana Vasquez: Emmy-winning host and TV personality Lilliana Vazquez is a trailblazing interviewer, style expert, and producer. With roles in front of and behind the camera, she's built an inspiring career watched by millions across numerous platforms. At barely five feet tall, Vazquez brings a larger than life presence to everything she does - her upbeat personality and approachable style combined with her natural ability to connect with audiences have made her a household name. Most recently, Vazquez was the host of E! Entertainment's daily morning shows E! News and Pop of the Morning, the first and only Latina to hold the role in the show's 30 year history. Previously, Vazquez was a contributor on TODAY where she shared her experiences and expertise covering the latest in technology, business, travel, entertainment, and lifestyle. She currently contributes to select programs like CBS Mornings and Amazon Live, while focusing on her newest role as a founding partner at Curated Productions. For more exclusive content and access to Lilliana's world, be sure to check out The LV Guide. About Nintendo: Nintendo Co., Ltd., headquartered in Kyoto, Japan, has created franchises that have become household names worldwide, including Mario ™, Donkey Kong ™, The Legend of Zelda ™, Metroid ™, Pokémon ™, Animal Crossing ™, Pikmin ™ and Splatoon ™, through its integrated hardware and software products. Nintendo aims to deliver unique, intuitive entertainment experiences for everyone, manufacturing and marketing video game devices such as the Nintendo Switch ™ family of systems, developing and operating applications for smart devices, and collaborating with partners on a range of other entertainment initiatives like visual content and theme parks. Nintendo has sold more than 5.4 billion video games and over 800 million hardware units globally. From the launch of the Nintendo Entertainment System ™ more than 30 years ago, through today and into the future, Nintendo’s continuing mission is to create unique entertainment that puts smiles on the faces of people all over the world. A wholly owned subsidiary, Nintendo of America Inc., based in Redmond, Wash., serves as headquarters for Nintendo’s operations in the Americas. For more information about Nintendo, please visit the company’s website at https://www.nintendo.com/. Contact Details YourUpdateTV +1 212-736-2727 yourupdatetv@gmail.com
December 01, 2022 01:10 PM Eastern Standard Time
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News ReleaseSara Wingate Bako Honored by University of South Carolina College of HRSM with 2022 Distinguished Alumni and Friends of the College Award
YourUpdateTV
Sara Wingate Bako earned her degree in retailing from the University of South Carolina in 2004. Today she serves as president of London Times, a division of Maggy London Group. Four University of South Carolina alumni have been recognized by the College of Hospitality, Retail and Sport Management for their leadership and accomplishments in their field. The College of HRSM Distinguished Alumni and Friends of the College Awards are presented annually and celebrate industry professionals, organizations and friends of the college who are making an impact on the industry or who are helping to advance the College of HRSM’s education excellence. Congratulations to Sara Wingate Bako, 2022 College of HRSM Distinguished Alumni and Friends of the College award winner. Sara Wingate Bako earned her degree in retailing from the University of South Carolina in 2004. Today she serves as president of London Times, a division of Maggy London Group – a women’s designer apparel brand specializing in dresses. Throughout her distinguished career, Bako has remained engaged with her alma mater – providing mentorship and career development opportunities for students and serving on the Industry Advisory Board for the Department of Retailing. Career Highlights Prior to joining Maggy London in 2022, Bako spearheaded the launch and oversaw management of three brands; Cupio, Cupio Blush, and Adyson Parker. Bako has held numerous executive positions with companies such as Takeout Inc., HMS Productions, and NYC Alliance. Her retailing career started in 2005 in the executive training program with Macy’s where she went on to become a buyer before moving to New York City to pursue wholesale and merchandising. She is a member of two exclusive leadership groups, Chief and the Women in Retail Leadership Circle. HRSM Distinguished Friend of the College Award: Contemporary Services Corporation Established in 1967, Contemporary Services Corporation, CSC is the world leader in crowd management and event security. CSC’s esteemed clientele base includes more than 180 stadiums, arenas, and theaters, over 110 universities and scholastic institutions, nearly 50 convention centers, and numerous clients within the professional ranks of MLB, MLS, NBA, NFL, NHL, and NASCAR. CSC has also provided services for the world’s most prestigious special events, including Collegiate Bowl Games, NCAA Final Four Tournaments, Ryder Cup, Presidents Cup, Kentucky Derby, 32 Super Bowls, 10 Olympic Games, 5 Presidential Inaugurations, 4 Papal Visits, and 2 FIFA World Cups. CSC operates 49 branch locations throughout the United States and Canada and has a long-standing partnership with the University of South Carolina. Numerous South Carolina graduates are currently working in various managerial positions with CSC. CSC provides South Carolina students with unique opportunities to gain event experience at the largest sporting events, including the Super Bowl, MLB All-Star Events, PGA Championship, Ryder Cup, Players Championship, Presidents Cup, Kentucky Derby and many more. Contact Details YourUpdateTV +1 212-736-2727 yourupdatetv@gmail.com
December 01, 2022 11:00 AM Eastern Standard Time
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News ReleaseHong Kong Baptist University-led research facilitates more efficient hybrid rice breeding with pioneering female sterility technique
Hong Kong Baptist University
HONG KONG SAR - Media OutReach - 1 December 2022 - Research led by Hong Kong Baptist University (HKBU) involving the use of a pioneering female sterility technique has led to a breakthrough in the production of hybrid rice seeds. Compared to the commonly used “three-line” male sterility technique in hybrid rice seeds production, the novel approach enhances the efficiency of hybrid rice production by eliminating rice seeds that have been produced due to the self-pollination of the “restorer line”. The novel technique enables fully automatic harvesting of hybrid seeds by machines, which can substantially reduce harvesting costs. A research team led by Professor Zhang Jianhua, Chair Professor of the Department of Biology at HKBU explores female sterility technique for hybrid rice breeding. The research results have recently been published in Cell Research, a top-ranking international scientific journal. Male sterility technique incurs high harvesting costs Self-pollinating plants are known to maintain their genome homozygosity, and as a result, their offspring can have the same features over generations. Heterosis, which refers to the increased rate of growth due to genome heterozygosity as a result of the hybridisation of distant parents, is difficult to exploit with self-pollinating plants. In nature, rice is usually bred using self-pollination. However, over the past few decades, scientists – following pioneering work by Professor Yuan Longping, the “Father of Hybrid Rice” – have developed hybrid rice breeding techniques by exploiting sterile male genes, and these techniques can produce hybrid seeds with the normally self-pollinating rice plants in large quantities. China and other countries around the world have extensively used the male sterility technique to produce hybrid rice seeds, and it has led to a substantial increase in rice yields. The male sterility technique first breeds cultivars, i.e. plant varieties, of the “male-sterile line” of rice as pollen receivers. Rice cultivars from the “restorer line” with normal fertility act as pollen donors, and they are grown close to the “male-sterile line” to facilitate pollen transfer for hybridisation. However, self-pollinating seeds can also be produced by the “restorer line”, and they must be removed manually to avoid mixing them up with the hybrid seeds before mechanical harvest, resulting in high harvesting costs. In theory, using sterile female rice as the “restorer line” is ideal because it cannot produce any self-pollinated seeds. However, this approach has not been adopted because the germplasm of sterile female rice remains extremely rare in nature and sterile female plants find it difficult to self-reproduce. TFS1 mutation exhibits female sterility After nearly a decade of ongoing study, a research team led by Professor Zhang Jianhua, Chair Professor of the Department of Biology at HKBU, has managed to identify a “spontaneous thermo-sensitive female sterility 1” (TFS1) gene mutation in an elite rice cultivar during paddy field production. This genetic mutation exhibits female sterility under regular or high temperature conditions (i.e. above 25°C), and fertility is partly resumed under low temperature conditions (i.e. 23°C). It does not have any defects in terms of its vegetative growth. The team observed that rice with the TFS1 gene mutation can produce healthy pollen with normal male fertility. Rice with normal fertility can produce normal seeds after receiving pollen from rice with the TFS1 gene mutation. Further investigations revealed that under regular or high temperature conditions, after pollen has landed on the stigma of rice with the TFS1 gene mutation, pollen tubes that have grown from the pollen cannot enter the embryo sac. The embryos therefore fail to develop and seeds cannot be produced. But under low temperature conditions, the ability to fertilise and develop embryos is partially recovered. Following genetic analysis using gene cloning and molecular techniques, the team found that the female sterility mutation is created by a point mutation in the genic region of Argonaute7 (AGO7), a member of the Argonaute (AGO) protein complex that is responsible for the production of many small interfering RNAs, namely tasiR-ARFs. The downstream regulation of these tasiR-ARFs regulates the pollen tube entrance into the embryo sac, but it failed under regular or high temperature conditions in the rice with TFS1 mutation, and hence double fertilisations cannot be achieved. No need to remove “restorer lines” before harvest To evaluate the potential of using TFS1 as a genetic tool for hybrid rice production, the team conducted field trials in Hong Kong and Hunan Province in mainland China. The TFS1 gene mutation was introduced into three cultivars of rice by introgression and genome editing to create the germplasms with thermo-sensitive female sterility. They acted as the “restorer lines” for pollen donation. Another three cultivars of rice with male sterility were used as the “male-sterile lines”. The team planted the “restorer lines” separately next to the “male-sterile lines” as in traditional hybrid breeding, or randomly mixed them on the farm when planting. In both planting arrangements, more than 30% of the panicles of the “male-sterile lines” in Hong Kong, and 40% in Hunan Province produced hybrid seeds. The proportion of seed sets is similar to the hybrid production yields using existing “restorer lines”, but the hybrid rice seeds can be harvested without the removal of the “restorer lines”. Great commercial potential with reduced harvesting costs Professor Zhang said: “Nowadays, producing hybrid rice seeds is still a labour-intensive process in agriculture. Female sterility, if it can be introduced into a ‘restorer line’ as a pure pollen donor, has great potential to reduce the cost, because the male and female parents of hybrid rice can be grown and harvested together by machines without worrying about seed purity. “Our research findings provide a suitable trait for fully mechanised hybrid rice breeding, and our genetic tool has shown great promise for commercial applications. To maximise rice yields, we need further large-scale field trials to improve the receptibility between female and male-sterile lines.” Apart from researchers from HKBU, the research team included scientists from the Hunan Agricultural University, the Guangdong Academy of Agricultural Sciences, the University of California at Davis, and the National Agriculture and Food Research Organisation in Japan. Contact Details Communication and Public Relations Office Winnie Shum +852 3411 5262 hkbunews@hkbu.edu.hk
December 01, 2022 05:16 AM Eastern Standard Time
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News ReleaseDesign from Taiwan Shines Worldwide
Taiwan International Student Design Competition
TAIPEI, TAIWAN - Media OutReach - 30 November 2022 - Organized by the Ministry of Education and being the largest-scale global design contest for students nowadays, Taiwan International Student Design Competition was initiated back in 2008 and is marking its 15th anniversary this year, in 2022. TISDC has now been widely recognized by the global design community as being both prestigious and credible and has served as the best example of the Ministry of Education’s success in promoting design education. The Competition has three categories: Product Design, Visual Design, and Digital Animation. The theme of this year’s edition, “One World,” resonates with the Sustainable Development Goals (SDGs) of the United Nations and emphasizes the core spirit of the world as one family towards global sustainability. Students are expected to face and reflect on issues related to sustainability, incorporate the concepts of the SDGs into their works, and fulfill their responsibilities as global citizens. A group photo from the award ceremony of 2022 Taiwan International Student Design Competition The 2022 Taiwan International Student Design Competition held its award ceremony at Eslite Performance Hall in Songshan Cultural and Creative Park in Taipei City on November 29, 2022. This year, a total of 16,749 participating entries came from 867 school departments in 66 countries/regions. The composition of the jury panel was highly international. During the preliminary selection, 587 works were shortlisted by 112 professionals from 31 countries around the world, with 56 jurors from Taiwan and 56 from abroad, respectively (The ratio of domestic to foreign jurors was 50%:50%). As for the final selection, the jury panel consisted of 45 professionals from 28 countries, with 39 of them being international jurors and only 6 from Taiwan (The international jurors accounted for 80%, while the domestic ones 20%). Eventually, 77 works were picked as winners. The low finalist rate of 3.6% and the even lower winning rate of 0.4% highlight the preciousness of the winning entries, which have stood out to win the following prizes: 1 grand prix of the year and 1 gold, 1 silver, 3 bronzes, and 12 honorable mentions for each category (financed by the Ministry of Education); 22 international design association special prizes (jointly sponsored by iSee Taiwan Foundation and Sayling Wen Cultural & Educational Foundation); 3 Environmental Sustainability Award prizes (established by TPCA Environment Foundation). Since 2015, TISDC has received the sponsorship of iSee Taiwan Foundation and Sayling Wen Cultural & Educational Foundation to cooperate with 22 international design associations. These global design partners are located across the five continents of Europe, Americas, Asia, Africa, and Oceania, and they all enjoy high reputation and a large scale. The 22 organizations, which have authorized the establishment of international design association special prizes in TISDC, include Cumulus, International Council of Design (ICoD), World Design Organization (WDO), The Bureau of European Design Associations (BEDA), Pan Afrikan Design Institute (PADI), International Poster Biennial in Mexico (IPBM), among others, and the winners of these international design association special prizes this year came from Poland, India, Thailand, the United States, Taiwan, etc. Through such a cooperation mechanism, an international design exchange platform has been built, which can expand the influence of design from Taiwan, allow Taiwan to be seen through design, and provide young students worldwide with a stage where they can shine and unleash great potential. In addition, TISDC has cooperated with the International Poster Biennial in Mexico (BICM) this year. By setting up a TISDC special prize in this competition, TISDC enjoys the opportunity to be co-listed with the United Nations Development Program and Amnesty International, which helps advance TISDC towards its goal of further internationalization and branding. Contact Details Media Contact Miira Lin mengchihlin@asia.edu.tw
November 30, 2022 09:00 AM Eastern Standard Time
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News ReleaseExpansion of Pipeline to Mental Health
The Chicago School of Professional Psychology
Nearly half of U.S. psychologists in a new survey say they cannot meet the growing demand for services and three-quarters say they have longer waiting lists than before the pandemic. “This new survey confirms what we have already heard from patients: people are having a hard time accessing the mental health services they need,” said Dr. Michele Nealon, Psy.D., President of The Chicago School of Professional Psychology. “It is critical now more than ever to expand the pipeline for mental health professionals and promote integrated behavioral health into primary care.” The 2022 COVID-19 Practitioner Impact Survey of 2,300 psychologists by the American Psychological Association found that demand for treatment of anxiety and depression remained high for the third consecutive year, along with increased demand for treatment of trauma-related disorders, increased stressors, and substance use disorders. Six in 10 practitioners said they had no more openings for new patients, nearly half (46%) said they had been unable to meet treatment demand and nearly three quarters (72%) have longer waiting lists than before the pandemic. On average, psychologists reported being contacted by more than 15 potential new patients seeking care per week. Nearly eight in 10 psychologists (79%) said they had seen an increase in the number of patients with anxiety disorders since the start of the pandemic, and 66% had seen an increase in the demand for treatment for depression. Almost half (47%) said they had seen an increase in demand for addiction treatment (compared to 43% last year) and 64% had seen an increase in demand for trauma treatment (compared to 62% last year). 2021). Additionally, two-thirds of psychologists reported seeing an increase in symptom severity among patients in 2022. “The social, emotional, and economic effects of a pandemic are still with us and will be for quite some time. In addition, the stressors associated with inflation, social and racial inequities, political upheaval, and international tensions are creating an unsettled nation. At a time when mental health services are needed the most, we are struggling the most to meet those needs,” said Dr. Nealon. “Policy makers have to make a bigger investment in financial and programmatic support to ensure that everyone who seeks psychological services can find a professional who can understand and help them.” About The Chicago School of Professional Psychology: Integrating theory with hands-on experience, The Chicago School of Professional Psychology provides education rooted in a commitment to innovation, service, and community for thousands of diverse students across the United States and globally. Founded in 1979, the nonprofit, regionally accredited university now features campuses in iconic locations across the country (Chicago, Southern California, Washington, D.C., New Orleans, Dallas) and online. To spark positive change in the world where it matters most, The Chicago School has continued to expand its educational offerings beyond the field of psychology to offer more than 30 degrees and certificates in the professional fields of health services, education, counseling, business, and more. Through its engaged professional model of education, commitment to diversity and inclusion, and an extensive network of domestic and international professional partnerships, The Chicago School’s students receive real-world training opportunities that reflect their future careers. The Chicago School is proud to be a part of TCS Education System, a nonprofit, integrated system of colleges and universities that works collaboratively to advance student success and community impact. To learn more, visit www.thechicagoschool.edu. Contact Details Kelton Gibson +1 661-607-2012 kgibson1@thechicagoschool.edu
November 28, 2022 10:55 AM Pacific Standard Time
News ReleaseVolatus Aerospace Expands Product Distribution to US Market with Acquisition of Empire Drone Company LLC.
Volatus Aerospace Corp.
Volatus Aerospace Corp. (TSXV: VOL) (OTCQB: VLTTF) (“Volatus” or “the Company”) announced today that it has signed an arm’s length definitive agreement to acquire Syracuse-based Empire Drone Company LLC., one of North America’s fastest-growing distributors and integrators for unmanned aerial systems. With Fortune Business Insights projecting the commercial drone market to grow to $47.38 billion by 2029 at a CAGR of 28.58%, the addition of Empire Drone in the USA positions Volatus to capitalize on this opportunity by adding to its growing global presence in key markets for green drone technologies, which includes Volatus Aerospace LATAM in South America, Omniview Tech in Canada, and iRed Remote Sensing in the UK. “Volatus is already a major distributor and developer of civil and defence drone solutions in Canada,” said Glen Lynch, CEO of Volatus Aerospace. “The addition of Empire Drone solidifies our footprint in America and positions us for improved margins and accelerated growth in America with a US depot and US-based support.” “Joining Volatus provides Empire with the resources needed to accelerate our growth,” said Sean Falconer, CEO and founder of Empire. “We’ll become a more important partner for our existing OEM suppliers and increase our offering with Volatus technologies such as the Aerieport remote nesting station, Hydra Crawler, and other Volatus defence and public safety products. It’s long been my goal to be a dominant player in the United States and this deal will give me the resources needed to get there.” Empire Drone is expected to generate revenue of C$2.5M in 2022 with a 6% EBITDA margin. Under the terms of the agreement, Volatus will purchase 100% of the company for a cash consideration of US$300,000, equity of US$350,000 with a minimum floor price of $0.65, and earn out of US$350,000 paid in equity after one year anniversary based on the 30-day volume weighted average price (VWAP) with a minimum floor price of $0.65 per share and assume the long-term debt of US$225,000. This announcement marks another step in a series of interrelated commercial milestones intended to drive and scale the commercialization of drone technologies including: Announcement of Volatus Aerospace LATAM, a joint venture with EOLO Drones S.A.C. ("EOLO") to expand Volatus' commercial operations in Latin America. Introduction of a full-service financing program for enterprise and industrial drone equipment to help drone service providers, public safety agencies and industrial clients leverage the rapid evolution of related technologies by offering rental, usage contracts, and customized funding arrangements for the sale of its Drone Solutions targeted at transactions valued from $25,000 to over $2,000,000. Acquisition of iRed Remote Sensing based in Emsworth, England to provide a foundation for continued growth in the UK. The acquisition of Empire Drone is scheduled to close on December 31st conditional on satisfactory completion of due diligence, approval of the respective Board of Directors, and regulatory approval by the Toronto Stock Exchange. About Volatus Aerospace: Volatus Aerospace Corp. is a leading provider of integrated drone solutions throughout North America and growing into Latin America and globally. Volatus serves civil, public safety, and defense markets with imaging and inspection, security and surveillance, equipment sales and support, training, as well as R&D, design, and manufacturing. Through our subsidiary, Volatus Aviation, we are introducing green and innovative drone solutions to supplement and replace traditional aircraft and helicopters for long-linear inspections such as pipeline, energy, rail, and cargo services. Volatus is committed to carbon neutrality; the fostering of a safe, equitable and inclusive workplace; and responsible governance. Forward-Looking Information This news release contains statements that constitute “forward-looking information” and “forward-looking statements” within the meaning of applicable securities laws, including statements regarding the plans, intentions, beliefs, and current expectations of the Company with respect to future business activities and operating performance. Often, but not always, forward-looking information and forward-looking statements can be identified by the use of words such as “plans”, “expects”, “is expected”, “budget”, “scheduled”, “estimates”, “forecasts”, “intends”, “anticipates”, or “believes” or variations (including negative variations) of such words and phrases, or statements formed in the future tense or indicating that certain actions, events or results “may”, “could”, “would”, “might” or “will” (or other variations of the foregoing) be taken, occur, be achieved, or come to pass. Forward-looking information includes information regarding: (if) the business plans and expectations of the Company; and (ii) expectations for other economic, business, and/or competitive factors. Forward-looking information is based on currently available competitive, financial, and economic data and operating plans, strategies, or beliefs as of the date of this news release, but involve known and unknown risks, uncertainties, assumptions and other factors that may cause the actual results, performance or achievements of the Company to be materially different from any future results, performance or achievements expressed or implied by the forward-looking information. Such factors may be based on information currently available to the Company, including information obtained from third-party industry analysts and other third-party sources, and are based on management’s current expectations or beliefs. Any and all forward-looking information contained in this news release is expressly qualified by this cautionary statement. Investors are cautioned that forward-looking information is not based on historical facts but instead reflects expectations, estimates or projections concerning future results or events based on the opinions, assumptions and estimates of management considered reasonable at the date the statements are made. Forward-looking information and forward-looking statements reflect the Company’s current beliefs and is based on information currently available to it and on assumptions it believes to be not unreasonable in light of all of the circumstances. In some instances, material factors or assumptions are discussed in this news release in connection with statements containing forward-looking information. Such material factors and assumptions include, but are not limited to: the commercialization of drone flights beyond visual line of sight and potential benefits to the Company; the completion of the Offering; meeting the continued listing requirements of the TSXV; and anticipated and unanticipated costs and other factors referenced in this news release.” Although the Company has attempted to identify important factors that could cause actual actions, events or results to differ materially from those described in forward-looking information, there may be other factors that cause actions, events or results to differ from those anticipated, estimated or intended. The forward-looking information contained herein is made as of the date of this news release and, other than as required by law, the Company disclaims any obligation to update any forward-looking information, whether as a result of new information, future events or results or otherwise. There can be no assurance that forward-looking information will prove to be accurate, as actual results and future events could differ materially from those anticipated in such statements. Accordingly, readers should not place undue reliance on forward-looking information. Neither the TSXV nor its Regulation Services Provider (as that term is defined in the policies of the TSXV) accepts responsibility for the adequacy or accuracy of this news release. Source: Volatus Aerospace Corp. TSXV: VOL Contact Details Abhinav Singhvi +1 514-447-7986 abhinav.singhvi@volatusaerospace.com Company Website https://volatusaerospace.com
November 28, 2022 06:30 AM Eastern Standard Time
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News ReleaseHKBU joint research develops multifunctional nanoparticle for diagnosis and treatment of glioma
Hong Kong Baptist University
HONG KONG SAR - Media OutReach - 25 November 2022 - A Hong Kong Baptist University (HKBU) collaborative research team has synthesised a nanoparticle named TRZD that can perform the dual function of diagnosing and treating glioma in the brain. It emits persistent luminescence for the diagnostic imaging of glioma tissues in vivo and inhibits the growth of tumour cells by aiding the targeted delivery of chemotherapy drugs. The nanoparticle offers hope for the early diagnosis and treatment of glioma, especially cerebellar glioma, which is even harder to detect and cure with existing methods. The research team led by Dr Wang Yi, Assistant Professor of the Department of Chemistry at HKBU, has developed a near-infrared persistent luminescence nanoparticle named TRZD for the diagnosis and treatment of glioma. The research results have been published in Science Advances, an international scientific journal. Limitations of existing diagnostic and therapeutic approaches Glioma is the most common form of malignant primary brain tumour, and it accounts for about one-third of all brain tumours. Magnetic resonance imaging (MRI) is commonly used to diagnose glioma, but the technology is not that sensitive. Cerebellar glioma, a relatively rare brain tumour, is even harder to detect with MRI. To facilitate early detection and treatment, an alternative method with improved sensitivity and precision is needed to diagnose glioma. Doxorubicin, a chemotherapy agent, is an effective treatment for glioma. However, its application may also damage normal cells, and it is associated with a range of side effects. To enhance doxorubicin’s clinical efficacy and minimise its side effects, a novel approach is needed to apply the drug to tumour cells in a more targeted manner. In response to the diagnostic and therapeutic needs of glioma, a research team co-led by Dr Wang Yi, Assistant Professor of the Department of Chemistry at HKBU, and Professor Law Ga-lai, Professor of the Department of Applied Biology and Chemical Technology at the Hong Kong Polytechnic University, has synthesised a novel near-infrared (NIR) persistent luminescence nanoparticle called TRZD, which can play a dual role in diagnostic imaging and as a drug carrier for glioma. TRZD has the characteristic of emitting NIR persistent luminescence after excitation with ultraviolet (UV) light. The basic structure of TRZD is a combination of nanoparticles, loaded with the mesoporous structure of silica, which makes it a good carrier of doxorubicin particles. Its surface is coated with red blood cell membranes to increase its stability, and it is embedded with T7 peptides. T7 peptides have a strong affinity for transferrin receptors which are abundant on the surface of tumour cells, and they can facilitate TRZD’s penetration through the blood-brain barrier. An imaging probe for glioma diagnosis The research team evaluated the efficacy of TRZ (i.e. TRZD without doxorubicin) in diagnostic imaging for glioma with a mouse model. TRZ particles were first excited by UV light to initiate luminescence. Mice with tumour tissues injected into their cerebrum and cerebellum were then treated with TRZ. In the following 24 hours, TRZ luminescence was detected at the tumour sites of the mice. However, when the same experiment was conducted with TRZ without T7 peptides, and TRZ without both the red blood cell membrane coating and T7 peptides, no luminescence was detected at the tumour sites of the mice. The results show that the red blood cell membrane coating can prolong the function of TRZ by stabilising the nanoparticle, and it can slow down its natural uptake by the human body. On the other hand, T7 peptides are instrumental in TRZ’s penetration into and accumulation in tumour cells, so that it can perform its imaging function for glioma. Dr Wang said: “Our experiment suggests that TRZ is a promising bioimaging agent for the diagnosis of glioma. It was observed that TRZ’s luminescence can be detected in tumour cells in both the cerebrum and cerebellum regions of the brain, which is an encouraging result because glioma in the cerebellum region is difficult to detect with existing diagnostic methods. As a result, TRZ offers new hope for the timely and accurate diagnosis of glioma.” TRZD inhibits the growth of glioma and extends the lifespan of mice The research team further evaluated the anti-tumour efficacy of TRZD using a group of mice who had had their cerebrum and cerebellum injected with tumour tissues. After applying TRZD for 15 days, the average diameter of their tumours was reduced to 1 mm. They also survived 20 days longer on average compared to the control group, who had not received TRZD. Besides, cell death was observed in the tumour region but not in normal brain tissue. Dr Wang said: “The experimental results indicate that TRZD’s therapeutic effect on glioma has good selectivity, because doxorubicin is brought specifically to tumour cells due to T7 peptide’s strong affinity with tumour cells’ surface receptors and its ability to penetrate the blood-brain barrier. As a result, doxorubicin can be applied in a more targeted manner, and hopefully its side effects can be minimised with a reduced drug dosage. “We concluded that TRZD demonstrates promising potential, and it could be developed into a new generation of anti-glioma drugs that can perform the dual function of diagnosis and treatment. It also offers hope for the development of treatment protocols for other brain diseases.” Contact Details Winnie Shum +852 3411 2119 hkbunews@hkbu.edu.hk
November 25, 2022 08:00 AM Eastern Standard Time
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News ReleaseBetter Brain Health and Parkinson’s Disease: Recognizing Symptoms, Taking Control of Your Health
YourUpdateTV
A video accompanying this announcement is available at: https://youtu.be/m_aCzxxxWh4 Recent advancements in science show that there is so much you can do as you age to boost brain health. From diet and exercise to social connection, research is piecing together the puzzle of how to best care for your brain to help prevent neurological disease, and how to treat it if it develops. A newly expanded research study from the Michael J. Fox Foundation, The Parkinson’s Progression Markers Initiative (PPMI), is helping scientists better understand what it means to be at risk for brain diseases such as Parkinson’s. Through important contributions from study volunteers – via online questionnaires and at clinical sites around the country -- PPMI is revolutionizing what we know about Parkinson’s today. Would it surprise you to learn that new research points to long-term smell loss as a potential indicator of Parkinson’s? Or, that people who are recently diagnosed with Parkinson’s are the most valuable contributors to this groundbreaking research? There is so much being done to better understand, identify and treat Parkinson’s – the world’s second most common brain disease. And PPMI is helping the field get closer than ever to answering those questions. The Study That Could Change Everything PPMI is on a mission to understand who is at risk for Parkinson’s, who gets it and why. The study’s recent expansion means that anyone over age 18 can help, regardless of whether you have Parkinson’s disease or not. The more people who join PPMI and share valuable health data online, the faster we can change everything about how brain diseases like Parkinson’s are diagnosed, treated and ultimately, prevented. For more information, and to join PPMI, visit michaeljfox.org/ppmi Contact Details YourUpdateTV +1 212-736-2727 yourupdatetv@gmail.com
November 23, 2022 07:00 AM Eastern Standard Time
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