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News Release Digital Asset Direct

Novidea Unveils Major Release of New Features and Capabilities Across its Global Insurance Management Platform

Novidea

Novidea, creator of the cloud-based, data-driven enterprise insurance management platform for brokers, agents, MGAs/MGUs, wholesalers, and carriers, today announced a major new release with significant enhancements to its award-winning insurance management platform. This release impacts multiple areas of the platform, delivering improvements and new efficiencies for users in every market served by the Novidea insurance management solution. The latest version of the Novidea platform includes enhancements to claims, billing, accounting, document management, quoting, submissions, UI/UX, and more. With this new release, Novidea delivers on its commitment to continually invest in innovation and maintain its competitive edge. To support this goal, the company has focused on significant talent acquisition, growing its employee count by 50% in the last twelve months. This latest release of the Novidea platform is future-forward and highly scalable, designed to help insurance organizations grow their businesses, expand into new lines of business, reach new markets, and deliver a more competitive customer experience. Some highlights of these new features include: Multi Legal Entity Enhancements - Data can be structured and organized in the platform with improved permissions and relevant access. With a single unified account, users can choose the relevant legal entity and use the system fully, enabling multiple businesses and divisions to operate on a single platform. Enhanced Policy Management Functionality - The platform has been enhanced with a more comprehensive quote-to-bind process. It now supports subjectivity management, processing of complex subscription market arrangements, premium payment warranty capture, creation of policy territory schedules, and an improved user journey for deduction & tax processing. Claims Management Enhancements - Including claim processing for various binder policy types, claims management has enhanced flexibility, enabling individual claim processing, providing direct settlement options, and enhancing claim financials for binder claims. User Experience Enhancements - A new, editable grid-based interface accelerates time-to-action for agents and brokers. This is a core component allowing users to edit values in-line, add and remove entries, all while leveraging smart calculations, and actions with every change. Dynamic Questionnaire - Insurance organizations can easily configure interactive forms to quickly and accurately capture customer data directly on their websites, and build in new lines of business. These flexible questionnaires are based on rules and logic to best address simple or complex form requirements. Enhanced Insurance Business Accounting (IBA) Functions - This release brings more efficient management of financial activities, including ad-hoc account statements, business query management, and automatic payment request process. Improved Line-of-Business (LOB) Management – The Direct Bill Statement Report now offers a simple, single-click report option to view all relevant commission data within a unified view, highlighting agency and policy information and commission tracking. IVANS Enhancements – Additional support for lines of business using IVANS policy and commission downloads greatly enhancing efficiency for insurance agencies. New Filing Module – The new release provides enhanced features to associate documents (such as files, emails, images, videos, etc.) to records, query for them and apply meta-data tagging, all within the Novidea platform. It offers seamless Outlook integration, and robust connectivity to customers’ document management systems. “Our latest release is the result of our continuous collaboration with our customers in advancing the insurance distribution industry into the digital age,” said Erez Nissim, CTO of Novidea. “We’re confident that our cloud-based, data-driven insurance platform will provide organizations with the technology and tools they need to manage complex transactions, stay ahead of the competition, build customer loyalty, and achieve growth.” Learn more about the Novidea enterprise insurance management platform live at InsureTech Connect 2023, October 31 - November 2, 2023, at the Mandalay Bay, Las Vegas – Booth #2320. About Novidea Novidea is the leading Insurtech provider of a cloud-native, data-driven insurance management system. Using an open API architecture, Novidea’s software platform enables brokers, agents, MGAs, and carriers to modernize and manage the customer insurance journey, end-to-end, and drive growth across the entire insurance distribution lifecycle. The Novidea platform, built to leverage the power of Salesforce’s Big Technology, provides a complete ecosystem spanning every aspect of an insurance business, including a 360-degree view of the customer and all stakeholders, enabling full integration between customer-facing policy transactions and the middle and back offices. Brokers, agencies, and MGAs extract more value from their customer and policy data with actionable intelligence from any device, anywhere. Novidea supports more than 100 customers across 22 countries. Contact Details Michelle Barry +1 603-809-2748 Michelle.barry@chameleon.co

November 01, 2023 08:00 AM Eastern Daylight Time

News Release

Binance Launches Native CHZ, Will BorroeFinance Rise To Compete With BNB?

Blockchain Digest

Top digital asset marketplace Binance has proclaimed its intention to support and integrate the Chiliz (CHZ) 2.0 network. Meanwhile, BorroeFinance ($ROE) continues to print green candles, leading investors to question whether $ROE could rise to compete with one of the top crypto coins, BNB. Can the new DeFi project contend with the established crypto? Let’s find out! >>BUY $ROE TOKENS NOW<< Binance Lists The Native Token of Chiliz On October 20, Binance, the world’s largest cryptocurrency exchange, announced that it would support the Chiliz 2.0 mainnet. This move marks a remarkable development for Chiliz (CHZ) and the blockchain and digital asset ecosystem as a whole. Accordingly, it will open up new possibilities for fan tokens, developers, and cryptocurrency enthusiasts. Alexandre Dreyfus, a well-known figure in the blockchain and cryptocurrency sphere, also notified the crypto community about the successful launch of the new Chiliz chain in partnership with Binance. Besides providing support, Binance intends to list its own CHZ token on the Chiliz 2.0 blockchain and help users move all listed fan tokens to the new chain as smoothly as possible. Binance’s decision to support the Chiliz chain integration is a major turning point, as it brings together one of the world’s leading cryptocurrency exchanges with a project that is revolutionizing fan engagement and tokenization. This partnership opens up new opportunities for developers and projects to create innovative products that leverage the power of fan tokens in tandem with established exchanges. The trading experience of users would become smoother as they migrate to the new Chiliz layer. Meanwhile, CHZ surged alongside other assets on the crypto market in the past week. Between October 16 and October 22, CHZ rose 11.61% from $0.056 to $0.062. Given the recent development in the Chiliz ecosystem and the ongoing rally in the crypto market, analysts expect CHZ to climb 6% higher from the current price of $0.066 to $0.070. BorroeFinance Prepares For A 167% Jump While Binance has made a move that could set the price of BNB on a trip to the top, investors are keen on knowing if $ROE can easily rival it. BorroeFinance is a new DeFi project represented by its native token, $ROE. Many chartists and crypto veterans believe in the potential of $ROE to set a precedent that tallies with other established assets, describing it as one of the best cryptocurrency investments to capitalize on. What makes BorroeFinance a project worth investing in is its real-time problem-solving capabilities. BorroeFinance serves as a marketplace for content creators and users of Web3 to connect with buyers interested in their creations. Here, they can tokenize their future invoices as NFTs and sell them at discounted prices. Also, BorroeFinance, through its advanced capabilities, offers solutions to the problems of traditional finance. As a top DeFi project focused on Web3, BorroeFinance ($ROE) integrates the core attributes of Web3. These characteristics include transparency, inclusivity, and decentralization. Another reason $ROE is dubbed the best crypto to buy is its presale projection. The token is currently trading at $0.015 in the second stage of its presale. With its target price for the presale cycle at $0.040, $ROE is set for a 167% liftoff to attain this level. >>BUY $ROE TOKENS NOW<< Bears Resist The Binance Coin (BNB) Although the latest move made by the crypto behemoth Binance is expected to affect its native token, BNB faces pushback at a pivotal level. Since retesting $228 on October 23, BNB hasn’t been able to surpass this level. The inability of BNB to exceed this level is due to heavy resistance at the $228 threshold. Notably, BNB began its ascent on October 16, rising from $209.8 to the current price of $226.9. During this timeframe, BNB recorded an 8.16% growth in price. This rally comes amid the ongoing recovery in the general market. Predicting the future of the Binance coin (BNB), experts have shared their perspectives on the potential price level for the asset. Analysts say that BNB could hit $243 if it escapes the bears at $228. That would require a 12.6% increase in the price of BNB from the current level for a further surge to be possible. Learn more about BorroeFinance ($ROE) here: Visit BorroeFinance Presale | Join The Telegram Group | Follow BorroeFinance on Twitter Contact Details Borroe Finance media@borroefinance.ai

October 31, 2023 04:35 PM Eastern Daylight Time

News Release

1606 Corp announces cutting-edge AI-driven CHATCBDW is live and in operation

1606 Corp.

1606 Corp CEO Greg Lambrecht joined Steve Darling from Proactive to share news the company has officially unveiled its cutting-edge AI chatbot, ChatCBDW, which represents a significant advancement in the world of CBD products and customer engagement. Lambrecht explained that ChatCBDW has undergone key designs and rigorous testing before being launched and is now live and operational. This innovative chatbot offers a wide range of user-centric features that go beyond the ordinary. One of its standout attributes is its capability to respond to user inquiries and provide comprehensive education on all aspects of CBD. However, ChatCBDW doesn't stop there. It takes personalization to the next level by offering tailored product recommendations to users and engaging in conversations that closely mimic human interaction. This level of innovation empowers customers to make well-informed choices, explore a diverse array of CBD products, and promises an unparalleled shopping experience within the CBD industry. The seamless integration of ChatCBDW with Microsoft Azure is a key component of its capabilities. Microsoft Azure is renowned for its scalability, unwavering reliability, and cutting-edge AI functionalities. This integration ensures that ChatCBDW can operate impeccably, even during periods of peak demand, delivering users a consistently responsive and seamless experience throughout their interaction with the chatbot. The company has also announced that Cool Blue Distribution is now a North American licensed reseller of ChatCBDW and is set to engage its network of over 800 CBD retailers immediately. The first direct-to-merchant marketing campaign is scheduled to begin by mid-November 2023, with the goal of generating notable revenue before January 1, 2024. Contact Details Proactive Canada +1 604-688-8158 na-editorial@proactiveinvestors.com

October 31, 2023 03:16 PM Eastern Daylight Time

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Limited-Time Promo! Complete P2P Tasks at HTX and Unlock Crypto Mystery Boxes Worth Up to $10,000

HTX

For those intrigued by digital assets, especially newcomers embarking on their cryptocurrency journey, your primary choice for P2P deposits should be HTX, a trusted and well-established cryptocurrency trading platform. Currently, HTX is rolling out a limited-time P2P promotion, offering an exciting opportunity for cryptocurrency users worldwide to engage and experience its variety of benefits. According to the exchange's official announcement, HTX P2P has introduced a time-limited promotion, "Complete P2P Tasks and Unlock Crypto Mystery Boxes". The event began on October 25 at 00:00 AM UTC and will continue until November 15 at 00:00 UTC, allowing participants to unlock Crypto Mystery Boxes potentially worth up to $10,000 by completing designated P2P tasks. The event is live! Join now to win Crypto Mystery Boxes, available for a limited time. The Unlock Crypto Mystery Boxes promotion is in full swing. The detailed rules for the event are listed below: Task 1: Earn a Crypto Mystery Box worth up to 100 USDT by reaching a cumulative P2P deposit volume of ≥100 USDT. Task 2: Earn a Crypto Mystery Box worth up to 1,000 USDT by reaching a cumulative P2P deposit volume of ≥800 USDT. Task 3: Earn a Crypto Mystery Box worth up to 500 USDT by completing the first P2P deposit with an amount of ≥ 200 USDT during the event period. Task 4: Earn a Crypto Mystery Box worth up to 100 USDT by joining the HTX Telegram group. Participants are required to complete level 3 KYC verification to claim the Crypto Mystery Box. By completing any designated P2P task on the event page, participants will receive a Crypto Mystery Box. Each Crypto Mystery Box holds a value of up to 1,000 USDT. For both Task 1 and Task 2, transaction amounts are calculated between 00:00 and 24:00 UTC, and they can be accumulated within the same day. The transaction amounts from the current day cannot be carried over to the next day. After 24:00 UTC, they will be reset to zero. Task 3 is limited to the first P2P deposit made during the event period. For the community task, participants need to fill out the corresponding Google form after joining the HTX Telegram group. Upon successfully finishing Tasks 1, 2, and 3, participants will receive the Crypto Mystery Boxes instantly. For the community task, data calculation will occur every Wednesday. After the calculation is complete, the Crypto Mystery Box will be credited to participants' HTX accounts within five working days. What makes HTX the top choice for P2P deposits? Which exchange will emerge as the top choice for global crypto investors? When it comes to P2P deposits, safety and convenience stand as the two essential benchmarks. As a well-established cryptocurrency trading platform, HTX has upheld a flawless record of asset security over the past decade. With robust technical capabilities and regular practice of publicly disclosing Proof of Reserves (PoR), HTX consistently maintains reserves that exceed 100% to ensure the security of user funds. The exchange also delivers a user-friendly and seamless trading experience, proving its reliability over the course of 10 years. Therefore, for newcomers and beginners venturing into the world of cryptocurrencies, HTX is the top choice. Recently, HTX was honored as the "Crypto Exchange Of The Year" at Blockchain Life 2023, a prominent summit in the blockchain industry. Notably, Justin Sun, a distinguished member of HTX's Global Advisory Board and the Founder of TRON, received the esteemed title of "Crypto Entrepreneur of the Year" during the same event. Since its rebranding in September this year, HTX has once again left a significant imprint on the global crypto arena, securing a crucial industry award. This underscores its strengthening foothold in the crypto market worldwide and its dedication to becoming a major player driving crypto's global development and adoption. For the next decade, HTX envisions an all-encompassing platform, including spot trading, derivatives trading, and wealth and asset management, becoming a trusted metaverse free port for global users in the Web3 era. About HTX Founded in 2013, HTX has evolved from a crypto exchange into a comprehensive ecosystem of blockchain businesses that span digital asset trading, financial derivatives, wallets, research, investment, incubation and other areas. HTX serves millions of users worldwide, with a business presence covering over 160 countries and regions across five continents. Its three development strategies - "global development, technology drives development, and technology for good" underpin its commitment to providing comprehensive services and values to global cryptocurrency enthusiasts. Contact Details Michael Wang glo-media@htx-inc.com Company Website https://www.htx.com/

October 31, 2023 02:56 PM Eastern Daylight Time

ARway.ai announces key collaboration with prestigious German technical university

ARway

ARway.ai chief product officer Shadnam Khan joined Steve Darling from Proactive to share news of a collaboration with the esteemed Institut für Innovations- und Informationsmanagement (iFii) to pioneer an innovative Augmented Reality navigation system on the iFii campus in Germany. This partnership signifies a significant development for ARway Corp and presents a promising growth opportunity. Khan emphasized that the collaboration with iFii, structured as a paid-partner deal, holds immense potential. Beyond the immediate project, it positions ARway to receive referrals from iFii to other institutions and businesses across the European Union. By showcasing this innovative AR navigation system on the iFii campus, ARway Corp is set to make a profound impact in the EU market. The joint venture with iFii encompasses a comprehensive roadmap aimed at harnessing the capabilities of augmented reality to create a smart campus. This partnership will transform the way faculty, students, and visitors experience the iFii campus by providing a seamless and intuitive AR experience. The AR-powered navigation system promises to revolutionize the way individuals interact with the campus environment, offering an innovative and user-friendly solution. Contact Details Proactive Investors Canada +1 604-688-8158 na-editorial@proactiveinvestors.com

October 31, 2023 02:03 PM Eastern Daylight Time

Video

NexTech3D.ai announces grand opening of office in Hyderabad, India

Nextech3D.AI

Nextech3D.ai CEO Evan Gappelberg joined Steve Darling from Proactive to share news the company has officially established its office space in Hyderabad, India, as part of a strategic initiative aimed at expanding profit margins and significantly reducing overhead costs. This move is expected to result in annual savings of up to $4 million for the company. Gappelberg noted that the initiative in Hyderabad will be led by Hareesh Achi, who brings valuable experience from his previous roles at Microsoft and Meta. Hyderabad is a particularly interesting location for this expansion because it has emerged as a powerhouse in the Indian start-up landscape, hosting a significant number of tech start-ups, totalling 4,369 from 2014 to 2023. This vibrant ecosystem offers great potential for Nextech3D.ai to thrive and expand its operations and aligns with its shift in focus. The company is now exclusively dedicated to high-scale production for its 3D modeling business, particularly in collaboration with Amazon and other enterprise accounts. Nextech3D.ai has transitioned away from serving small e-commerce clients that require a limited number of 3D models and is now prioritizing large enterprise clients, reflecting its commitment to growth and scalability. Contact Details Proactive Investors Canada +1 604-688-8158 na-editorial@proactiveinvestors.com

October 31, 2023 01:52 PM Eastern Daylight Time

Video

Passes’ CEO Lucy Guo Celebrates Her Birthday with Mega-Festival 'LUCYPALOOZA'

EMC

(Tuesday, October 31, 2023 - Los Angeles, CA) Passes hosted their annual exclusive ‘ Lucypalooza ’ celebrating Passes ’ CEO & founder, Lucy Guo ’s birthday, presented by Le Bon Argent by Floyd Mayweather, with partnering sponsors Flex, Betr and Cached, on Thursday, October 12th, 2023, in Los Angeles, CA. The ultra invite only party, produced by eventors, hosted a festival worthy lineup and fun shenanigans with the industry’s top creators and founders in the lifestyle & digital space. Attendees enjoyed specialty sips by Le Bon Argent, E11EVEN Vodka & Deleon Tequila, along with beverages by The Plug Drink and Monster Energy. Lucy Guo, CEO of Passes comments, “I was very excited that my closest family & friends came out to celebrate my birthday! I always love bringing an interesting, eclectic group together and this year was no different.” Party goers on site got to bounce through out the complex at each activation such as a flying money wind-grabbing machine by Flex, a boxing punch scoring machine by Betr, a ball pool by Cached, while Deleon Tequila’s ice sculpture bar had a crew of magician bartenders mixing specialty cocktails with playful presentations and tricks, and Monster Energy featured the live artist extraordinaire, Scratch Academy painting on old vinyl records. In addition to the muli-level festival experience, guests also indulged at the wellness hub with complimentary botox, hydrafacials and filler treatments by Upkeep, along with IV vitamin boost infusions by Drip IV Therapy. At the top of the hour before the clock struck midnight Le Bon Argent by Floyd Mayweather featured Lucy pouring over the champagne tower to ring in her birthday soiree with a toast and candle stacked birthday cake sing-off. Lucy and friends continued to party the night away with sounds by celebrity deejays, David Crow Ghastly, Diablo, Wax Motif, and Madds. Guo says, “ I’m thankful this year’s event was a success. Our goal was to have everyone celebrate with old friends, make new friends, and adopt some puppies - all of which happened! " Other notables that attended this year to celebrate Guo’s birthday were a variety of rising young hollywood reality tv star, to content creators, and celebrities such as Linzy Luu (Too Hot To Handle), Dre Woodward (Too Hot To Handle), Isaac Francis (Too Hot to Handle ), Bella Poarch (Singer ), Robert Graham (Bachelor in Paradise, Bachelorette), Joe Jenkins (Siesta Key), La Demi (TV Personality), Isaiah Harmison (Love Island), Georgenotfound, Sapnap, Colby Brock, Sam Golbach, Amber Mezner (Tik Toker), Anna Deguzman (America’s Got Talent), Bronny James, Nate Wyatt, and Wax Motif (Deejay). For the annual event, past VIPs attended and special guest performances included appearances by Ty Dolla $ign, Zedd, The Chainsmokers, John Summit, Tana Mongeau, G Eazy, Twan Kyuper, Georgia Hassarati, Dan Rhodes, Cray, Nick Hissom, Bryce Hall, Teala Dunn, Emma Norton, Adam Weitzman, Victoria Pass,xnY Emma Holzer, Keith Rabois, Matt Steffanina, Ian Somerhalder, David Dobrik, Francis Suarez, Casey Boonstra, Holly Scarfone and more. ### Passes Passes is a subscription platform that helps creators build their community and engage with their biggest fans. The company develops tools for the creator economy, allowing creators to monetize off of their exclusive content and IRL experiences. Passes was founded in 2022 and is located in Miami, Florida. For more information, please visit the website: www.passes.com and on Instagram: @joinpasses. Le Bon Argent From Epernay, France comes Le Bon Argent champagne and a no holds barred, Luxury Without Limits attitude. Quite simply, it is for those who seek the best in everything. The name Le Bon Argent literally translates to “Good Money” and just like the finest automobiles, yachts, & high fashion brands that surround Floyd, this Super-Premium Champagne is the very embodiment of the Mayweather lifestyle and all things luxurious. For more information, please visit: https://lebonargent.com/ Flex Flex is a finance super app that is revolutionizing business finance with credit cards, banking, payments, and insurance, all in one place. With a recent successful funding round of $120 million, Flex simplifies the back office experience into a seamless financial control hub. Experience the power of Flex with innovative offerings, including the Flex Credit Card, providing a 60-day interest-free period on all purchases and integrated employee expense management. Explore Flex Banking, offering up to a 4% yield on idle cash. Flex aspires to become the go-to financial platform for small businesses, empowering them to efficiently build, manage, and safeguard their financial futures. To Apply for Flex please visit: https://www.flex.one/ Betr Founded in 2022 by Joey Levy and Jake Paul, Betr is the fastest sports betting media brand in the U.S. and the first microbetting-focused gaming company that is pioneering a new way for fans to engage with sports. Microbetting allows users to bet on individual plays and events – pass or rush in football or if the next free throw will be good in basketball – rather than the outcome of a game. With its simple and intuitive user interface, Betr aims to solve a problem with traditional sportsbooks – a complicated and confusing user experience with numbers and odds that look more like a spreadsheet than a sportsbook. Since publicly launching its brand in August 2022, Betr has seen unprecedented growth while generating over 750 million impressions and 45 million engagements across its social channels. For more information, please visit: https://www.betr.app/. Cached – Your Data, Your Income: Cached is revolutionizing the $500 billion data economy by giving consumers the power to control and profit from the sale of their own data. Cached offers a groundbreaking smartphone app that allows consumers to continuously turn their data into a payout. By simply using their smartphones and sharing their preferences, habits, and interests, users can earn money every time their data is purchased by advertisers. For more information, please visit: https://mycached.com/. Contact Details EMC Brands Dianne Quirante dianne@emcbrands.com

October 31, 2023 01:13 PM Eastern Daylight Time

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Introducing the TechClusion Fund

Communication Service for the Deaf

CSD Social Venture Fund, a subsidiary of Communication for the Deaf, is proud to announce the launch of a new funding source for tech startups that prioritize inclusion and accessibility for deaf communities. The TechClusion Fund is a groundbreaking initiative that addresses a common oversight in technology development: accessibility. The fund was created with the intention of accelerating technology built by companies that create accessible products and services that benefit the Deaf community. Over the past 30 years, our society has experienced a rapid evolution in technological advancements. While these advancements generally improve our lives, we often see accessibility features added as an afterthought instead of being built into the original product design. This practice makes the user experience less than ideal for both those who do and do not use these features. “Accessible technology doesn’t just benefit Deaf communities,” explained Rosa Lee Timm, President of CSD Social Venture Fund. “When companies design their products with the needs of Deaf or disabled users in mind, they create a better experience for all users.” The TechClusion Fund was started with the intention of addressing these systemic and prevalent issues in tech by ensuring that entrepreneurs and developers are intentionally creating their products with all end-users in mind. “We expect that the impact of the TechClusion Fund will extend beyond the development of accessible products,” shared Greg Bland, Director of Business Development for CSD Social Venture Fund. “By focusing on startups who hope to have a positive impact on Deaf communities, we will see job creation and more opportunities for economic advancement for Deaf individuals.” Unlike CSD Social Venture Fund’s traditional VC funding, TechClusion is open to all tech-startups operating in the United States and not specifically Deaf-owned businesses. Applicants must demonstrate the following: How their work will positively impact Deaf communities. This can be through hiring Deaf and hard of hearing employees, Deaf ownership, or outlining how their product or service will contribute to deaf communities. A commitment to equitably hire Deaf, BIPOC Deaf, and other Deaf groups for various positions at levels of the company, including C-level positions, as the company grows. A commitment to both their company and TechClusion’s investment. For those who are interested in applying or learning more, you can visit CSD Social Venture Fund’s website or contact Rosa Lee Timm at svf@csdsvf.com for more information. CSD's Social Venture Fund is one of the only venture capital firms and incubators in the world supporting Deaf entrepreneurs and Deaf-owned and operated businesses. CSD SVF provides equity investments to Deaf-led businesses that exemplify CSD’s values: enhancing Deaf economic power, employing Deaf people, and creating social change. CSD SVF is committed to the success of each business, providing not only financial investment, but also access to tools and resources, enabling each Deaf-led business to thrive. Existing portfolio members include Mozzeria, National Deaf Therapy, DeafTax, Bus Door Films, Hands on Travel, Hotsy Totsy Haus, 4Legz All Natural Dog Treats and Lochiel Brewing. For more information, please visit https://csdsvf.com/ and follow us on Facebook, Twitter, Instagram, and LinkedIn. About Communication Service for the Deaf Communication Service for the Deaf (CSD) is the largest Deaf-led social impact organization in the world. For more than four decades, CSD has been a leader in creating and providing accessible and innovative solutions for the Deaf community. Today, CSD continues its work to create opportunities for personal and economic growth within the Deaf community, specifically addressing leadership and employment. For more information, please visit CSD and follow us on Facebook, Twitter, Instagram, and LinkedIn. Contact Details Communication Service for the Deaf Molly Miller +1 315-679-8948 mmiller@csd.org Company Website https://www.csd.org/

October 31, 2023 01:12 PM Eastern Daylight Time

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PathAI Announces Research Presentations at the Society for Immunotherapy of Cancer’s 38th Annual Meeting

PathAI

PathAI, a leading technology company which combines AI-powered pathology solutions with end-to-end central pathology and histology services, today announced it will present research underscoring the efficacy of PathExplore’s human interpretable features (HIFs) through three poster presentations at the Society for Immunotherapy of Cancer’s 38 th Annual Meeting on November 1-5 in San Diego, CA. The posters showcase how PathExplore provides high-resolution characterization of the tumor microenvironment (TME) through a standardized panel of HIFs derived from H&E whole slide images across multiple cancer types. Additionally, Incendia Therapeutics will present two posters reporting results that were generated utilizing PathExplore. “Building upon past publications and presentations, we continue to see the utility for histological features of the tumor microenvironment to further our understanding of disease biology, patient prognosis, and therapeutic response, which ultimately may lead to the discovery and implementation of novel biomarkers to advance precision medicine,” explained Mike Montalto, Ph.D., Chief Scientific Officer, PathAI. All three posters demonstrate the correlation between specific HIFs and established molecular measurements of the TME (e.g., gene expression profiles of specific cell populations), as well as specific HIFs and complex molecular signatures (e.g., immune phenotypes) which could better aid in the identification of patients eligible for targeted therapies, or result in the identification of new histology-based biomarkers. Quantifying the effect of microsatellite instability and mismatch repair deficiency on the tumor microenvironment (Poster 73) In this research, PathAI investigated the potential to predict and compare microsatellite stability and mismatch repair subtypes in colorectal and endometrial cancers utilizing PathExplore HIFs. The findings suggest MSS/dMMR tumors may warrant consideration for immunotherapy due to their TME’s similarity to microsatellite instability-high (MSI-H) and tumor mutation burden-high (TMB-H) solid tumors and AI-powered analysis of H&E WSI presents a more accessible and scalable method than current dMMR testing options. This poster will be presented by Judy Chen and Shima Nofallah on Friday, November 3 rd. Poster hall hours are 9 a.m. to 7 p.m. PT. Quantification of tumor infiltrating lymphocytes (TILs) from pathology slides reflects molecular immune phenotypes (Poster 122) In this research, PathAI deployed its PathExplore products on H&E WSI across eight cancer indications to extract HIFs quantifying the TME, including features that represent TIL fractions, densities, and distributions. Analysis revealed statistically significant correlations between TIL-associated HIFs with gene expression of known lymphocyte markers, as well as immune signature scores such as lymphocyte infiltration. These results show the predictive power that TIL-associated HIFs have for identifying immune phenotypes, as well as a promising direction for the discovery of histology-based immune biomarkers. This poster will be presented by Judy Shen on Saturday, November 4 th. Poster hall hours are 9 a.m. to 8:30 p.m. PT. Deep learning models identify key tumor microenvironment features associated with genetic signatures of UV metagenesis and alkylating agent treatment in melanoma (Poster 110) In this research, PathAI used PathExplore HIFs to investigate the association between TME features and mutational signatures indicative of UV mutagenesis, as well as alkylating agents-induced mutations. The results suggest that quantifying a tumor’s tissue and cellular composition can reveal meaningful information regarding the underlying mutation-driven or treatment-induced changes in the TME, which may have implications for therapy selection. This poster will be presented by Shima Nofallah on Saturday, November 4 th. Poster hall hours are 9 a.m. to 8:30 p.m. PT. Incendia Therapeutics (formerly known as Parthenon Therapeutics) posters In addition to the posters above, Incendia Therapeutics will present two posters on Friday, November 3 rd reporting results that were generated utilizing PathExplore. One poster (Poster 1287) compares PathExplore HIFs to mIF features and concluded that "TME models are a robust tool to distinguish tissue and cell features from H&E slides, comparable to mlF image analysis, but requiring less effort, time, and expense." In the second (Poster 1497), Incendia Therapeutics leveraged HIFs quantifying lymphocyte densities across cancer epithelium, cancer stroma, and the epithelial-stromal interface (ESI) to characterize barriers to lymphocyte entry into the cancer epithelium across immune phenotypes. More information on these posters can be found at https://www.incendiatx.com Please visit the PathAI booth, 615, to learn more and meet the team, or email us at bd@pathai.com. About PathAI PathAI is the only AI-focused technology company to provide comprehensive precision pathology solutions from wet lab services to algorithm deployment for clinical trials and laboratory use. Rigorously trained and validated with data from more than 15 million annotations, its AI-powered models can be leveraged to optimize the analysis of pathology samples to improve efficiency and accuracy of pathology interpretation, as well as to better gauge therapeutic efficacy and accelerate drug development for complex diseases. PathAI, which is headquartered in Boston, MA, and operates a CAP/CLIA-certified laboratory in Memphis, TN, is proud to have a team of 600+ innovative thinkers from around the globe. For more information, please visit www.pathai.com. Contact Details SVM Public Relations and Marketing Communications Maggie Naples +1 401-490-9700 pathai@svmpr.com Company Website https://www.pathai.com/

October 31, 2023 10:00 AM Eastern Daylight Time

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